Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1928 1
1947 1
1948 1
1949 1
1950 2
1951 2
1952 2
1953 4
1954 5
1955 1
1956 1
1957 2
1958 1
1959 2
1960 1
1961 1
1962 1
1963 6
1964 5
1965 3
1966 3
1967 2
1968 13
1969 13
1970 17
1971 14
1972 15
1973 24
1974 20
1975 44
1976 32
1977 40
1978 30
1979 38
1980 44
1981 57
1982 48
1983 75
1984 76
1985 64
1986 62
1987 53
1988 42
1989 45
1990 45
1991 39
1992 40
1993 41
1994 34
1995 30
1996 38
1997 29
1998 23
1999 18
2000 27
2001 22
2002 24
2003 21
2004 16
2005 19
2006 18
2007 21
2008 19
2009 18
2010 23
2011 23
2012 19
2013 18
2014 22
2015 21
2016 16
2017 15
2018 24
2019 24
2020 29
2021 20
2022 26
2023 21
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

1,700 results

Results by year

Filters applied: . Clear all
Page 1
Efficacy of phenobarbital and sodium valproate in treating convulsive epilepsy in rural northeast China.
Li J, Yang D, Zhao D, Li N, Lin W. Li J, et al. Seizure. 2019 Oct;71:207-213. doi: 10.1016/j.seizure.2019.06.012. Epub 2019 Jun 15. Seizure. 2019. PMID: 31394367 Free article.
PURPOSE: Phenobarbital and sodium valproate are broad spectrum and inexpensive antiepileptic drugs that are used to treat convulsive epilepsy. ...Efficacy of phenobarbital or sodium valproate was assessed by the reduction in seizure frequency. ...
PURPOSE: Phenobarbital and sodium valproate are broad spectrum and inexpensive antiepileptic drugs that are used to treat conv …
Parenteral antiepileptic/anticonvulsant drugs.
Mattson RH. Mattson RH. Neurology. 1996 Jun;46(6 Suppl 1):S8-13. doi: 10.1212/wnl.46.6_suppl_1.8s. Neurology. 1996. PMID: 8649613 Review.
A large number of drugs can be given parenterally for the control of acute seizures, although many of these compounds are associated with serious adverse effects. Phenobarbital, the first antiepileptic drug (AED), has long been available in an injectable formulation. The …
A large number of drugs can be given parenterally for the control of acute seizures, although many of these compounds are associated with se …
Stability of phenobarbital sodium diluted in 0.9% sodium chloride injection.
Nahata MC, Hipple TF, Strausbaugh SD. Nahata MC, et al. Am J Hosp Pharm. 1986 Feb;43(2):384-5. Am J Hosp Pharm. 1986. PMID: 3953601
The stability of phenobarbital sodium diluted to 10 mg/mL in 0.9% sodium chloride injection was studied at an unadjusted pH (8.5) and an adjusted pH (10.0) at 4 degrees C over a four-week period. ...The diluted phenobarbital sodium was stable ov …
The stability of phenobarbital sodium diluted to 10 mg/mL in 0.9% sodium chloride injection was studied at an unadjuste …
Treatment of epilepsy.
BAILEY AA. BAILEY AA. Can Med Assoc J. 1963 Jun 29;88(26):1284-9. Can Med Assoc J. 1963. PMID: 13969008 Free PMC article.
., three to six times a day, or acetazolamide (Diamox) 125-250 mg., three to four times a day. Phenobarbital is usually given as well to prevent grand mal seizures. Diphenylhydantoin sodium (Dilantin Sodium), 100 mg., and/or phenobarbital, 30-100 mg., …
., three to six times a day, or acetazolamide (Diamox) 125-250 mg., three to four times a day. Phenobarbital is usually given as well …
Anticonvulsant hypersensitivity syndrome.
Vittorio CC, Muglia JJ. Vittorio CC, et al. Arch Intern Med. 1995 Nov 27;155(21):2285-90. Arch Intern Med. 1995. PMID: 7487252
Anticonvulsant hypersensitivity syndrome is a potentially fatal drug reaction with cutaneous and systemic reactions (incidence, one in 1000 to one in 10,000 exposures) to the arene oxide-producing anticonvulsants--phenytoin, carbamazepine, and phenobarbital sodium. …
Anticonvulsant hypersensitivity syndrome is a potentially fatal drug reaction with cutaneous and systemic reactions (incidence, one in 1000 …
Drug therapy reviews: drug therapy of status epilepticus.
Browne TR. Browne TR. Am J Hosp Pharm. 1978 Aug;35(8):915-22. Am J Hosp Pharm. 1978. PMID: 150228 Review.
In managing tonic-clonic status epilepticus one should: (1) maintain vital functions at all times, (2) identify and treat precipitating factors and (3) administer an intravenous loading dose of phenytoin sodium or phenobarbital sodium. Careful use of i.v. dia …
In managing tonic-clonic status epilepticus one should: (1) maintain vital functions at all times, (2) identify and treat precipitating fact …
Effect of sodium valproate on phenobarbital serum levels in children and adults.
Fernandez de Gatta MR, Alonso Gonzalez AC, Garcia Sanchez MJ, Dominguez-Gil Hurle A, Santos Borbujo J, Monzon Corral L. Fernandez de Gatta MR, et al. Ther Drug Monit. 1986;8(4):416-20. doi: 10.1097/00007691-198612000-00006. Ther Drug Monit. 1986. PMID: 3103264
The influence of sodium valproate on serum levels of phenobarbital during combination treatment was studied in 29 children and 50 adults with epilepsy. ...Close monitoring of the serum levels of phenobarbital is recommended during simultaneous treatment with …
The influence of sodium valproate on serum levels of phenobarbital during combination treatment was studied in 29 children and …
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
Minagawa K, Miura H. Minagawa K, et al. Brain Dev. 1981;3(4):385-93. doi: 10.1016/s0387-7604(81)80067-8. Brain Dev. 1981. PMID: 6797314
Of 196 children with febrile convulsions, 6.9 were placed on phenobarbital, 4-5 mg/kg/day b.i.d., and 32 on primidone, 15-20 mg/kg/day b.i.d. ...This may be explained by the facts that when the same daily dosage of sodium valproate was given, the daily fluctuation o …
Of 196 children with febrile convulsions, 6.9 were placed on phenobarbital, 4-5 mg/kg/day b.i.d., and 32 on primidone, 15-20 mg/kg/da …
Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.
Haines C, Elcombe BM, Chatham LR, Vardy A, Higgins LG, Elcombe CR, Lake BG. Haines C, et al. Toxicology. 2018 Mar 1;396-397:23-32. doi: 10.1016/j.tox.2018.02.001. Epub 2018 Feb 6. Toxicology. 2018. PMID: 29425889
Phenobarbital (PB), a constitutive androstane receptor (CAR) activator, produces liver tumours in rodents by a mitogenic mode of action involving CAR activation. In this study, the hepatic effects of sodium phenobarbital (NaPB) were compared in male C57BL/6J …
Phenobarbital (PB), a constitutive androstane receptor (CAR) activator, produces liver tumours in rodents by a mitogenic mode of acti …
Pharmacokinetics and relative bioavailability of intramuscular phenobarbital sodium or acid in infants.
Minagawa K, Miura H, Chiba K, Ishizaki T. Minagawa K, et al. Pediatr Pharmacol (New York). 1981;1(4):279-89. Pediatr Pharmacol (New York). 1981. PMID: 7346748
Phenobarbital pharmacokinetics after a single intramuscular dose of approximately 10 mg/kg of phenobarbital sodium or acid were studied in twelve infants with febrile convulsions. The mean peak time after phenobarbital sodium (0.92 hr) was signi …
Phenobarbital pharmacokinetics after a single intramuscular dose of approximately 10 mg/kg of phenobarbital sodium or a …
1,700 results